Construction of the Health Center's main campus began in 1966. The main complex occupies a prominent hilltop near I-84 and the Farmington-West Hartford line. The massive, circular building originally contained about 1.2 million square feet, seven miles of corridors, and 2,000 rooms. Its first major addition, the Andrew J. Canzonetti, M.D. Building, was dedicated in 1994. It added 94,000 square feet next to John Dempsey Hospital. The Health Center's Academic Research Building opened in 1999. The impressive 11-story structure provides 173,647 square feet of modern laboratory space.
The Medical Arts and Research Building (MARB), which opened in 2005, added to the campus a four-story, 103,663 square-foot, facility for care and research related to conditions affecting bones, joints and connective tissue. The MARB houses an open MRI, physical therapy and rehabilitation services, as well as clinical services including orthopaedics, rheumatology, and an osteoporosis center. It also is home to the Farmington Surgery Center, a multispecialty outpatient surgery center.
In 2010, the Cell and Genome Sciences building added another 118,844 square feet to the UConn Health Centerís research enterprise. It houses research laboratories, offices, a 100-seat auditorium, cafeteria, and incubator space for businesses eager to commercialize stem cell science.
In all, the UConn Health Center campus in 2011 consists of 37 buildings totaling over 2.1 million square feet.
By 2018, Bioscience Connecticut will have transformed the UConn Health Center campus through the construction of a new patient care tower; renovations to the original research building, including a significant increase in incubator space; the construction of an outpatient patient care building; and renovations to the existing John Dempsey Hospital.